Endometriosis: Symptoms, Causes & Medication

Endometriosis is a chronic condition where tissue similar to the lining inside the uterus, called the endometrium, grows outside the uterus. This tissue can be found on the ovaries, fallopian tubes, the outer surface of the uterus, and other organs within the pelvis.

Symptoms

Common symptoms of endometriosis include:

  • Pelvic pain, often associated with menstrual periods
  • Pain during intercourse
  • Pain with bowel movements or urination
  • Excessive bleeding during periods (menorrhagia) or between periods (menometrorrhagia)
  • Infertility
  • Fatigue, diarrhea, constipation, bloating, and nausea, especially during menstrual periods

Causes

The exact cause of endometriosis is not known, but several theories exist:

  • Retrograde menstruation: Menstrual blood flows backward through the fallopian tubes into the pelvic cavity instead of leaving the body.
  • Embryonic cell transformation: Hormones such as estrogen may transform embryonic cells into endometrial-like cell implants during puberty.
  • Surgical scar implantation: After surgeries such as a hysterectomy or C-section, endometrial cells may attach to the surgical incision.
  • Immune system disorders: Issues with the immune system might make the body unable to recognize and destroy endometrial-like tissue growing outside the uterus.

Diagnosis

Diagnosing endometriosis typically involves:

  • Pelvic exam: A doctor feels for large cysts or scars behind the uterus.
  • Imaging tests: Ultrasound or MRI may help identify endometriosis.
  • Laparoscopy: A surgical procedure where a doctor views the inside of the abdomen with a camera and may take tissue samples for biopsy.

Treatment

Treatment for endometriosis can vary based on severity and includes:

  • Pain medication: Nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen can help reduce pain.
  • Hormone therapy: Hormonal contraceptives, gonadotropin-releasing hormone (Gn-RH) agonists, progestin therapy, and aromatase inhibitors can help control the growth of endometrial tissue.
  • Conservative surgery: Removal of endometrial tissue via laparoscopy can help alleviate symptoms and improve fertility.
  • Hysterectomy: In severe cases, removal of the uterus and possibly ovaries may be recommended.

Management and Lifestyle

  • Regular exercise
  • Heat application (e.g., heating pads)
  • Dietary changes (e.g., anti-inflammatory diet)
  • Stress management techniques such as yoga and meditation

Endometriosis can significantly impact the quality of life, but with proper management and treatment, many women find relief from symptoms and can lead fulfilling lives.


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